Will the Layla Mattress work on an adjustable base? Layla December 03, 2020 22:00 Updated Follow Yes. The Layla Mattress is an ideal choice for an adjustable base conforms perfectly in all adjustable positions. Related articles How do I unbox the Layla Mattress? How do I flip the Layla Mattress from the soft side to the firm side? What Base or Foundation can I use with the Layla Mattress? How do I know if I want a King or a Split King Adjustable Base? Can I wash the Mattress Cover? Comments 0 comments Please sign in to leave a comment.