Will the Layla Hybrid™ Mattress Work with an Adjustable Base? Layla December 17, 2020 15:28 Updated Follow Yes, due to the nature of the independently-moving springs, the Layla Hybrid™ Mattress has the flexibility to conform to an adjustable base with ease. Related articles What Base or Foundation Can I Use with the Layla Hybrid™ Mattress? Will the Layla Mattress work on an adjustable base? How Long Can the Layla Hybrid™ Mattress Stay Compressed in the Box Before Opening it? Does the Layla Adjustable Base™ work with any mattress? How long can the Layla Mattress stay compressed in the box before opening it? Comments 0 comments Please sign in to leave a comment.